Article Dans Une Revue Transplant Infectious Disease Année : 2019

Early necrotic skin lesions after a ABO‐incompatible kidney transplantation

Résumé

A 49-year-old man underwent ABO-incompatible kidney transplantation with a living donor. At day 33 post-transplantation, he presented with undiagnosed epilepsy with generalized tonic-clonic seizures. At day 44 post-transplantation, he developed left-sided pneumonia attributed to Aspergillus fumigatus and treatment with liposomal amphotericin B was initiated. At day 51 post-transplantation, necrotic skin lesions appeared. DNA sequencing in a fresh cutaneous biopsy finally identified Cunninghamella Spp., a member of the order Mucorales. Unfortunately, the necrotic lesions spread, and the patient died at day 60 post-transplantation. This case report highlights the infectious risk related to ABO-incompatible kidney transplantation and suggests a requirement for rapid identification of every skin lesion, even in the early phases of immunosuppression.
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Dates et versions

hal-03580069 , version 1 (18-02-2022)

Identifiants

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Julie Belliere, Marion Rolland, Emilie Tournier, Sophie Cassaing, Xavier Iriart, et al.. Early necrotic skin lesions after a ABO‐incompatible kidney transplantation. Transplant Infectious Disease, 2019, 21 (6), pp.e13173. ⟨10.1111/tid.13173⟩. ⟨hal-03580069⟩
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