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Article Dans Une Revue AJP - Endocrinology and Metabolism Année : 2023

The nervous system and adipose tissues: a tale of dialogues

Résumé

White, beige, and brown adipose tissues play a crucial role in maintaining energy homeostasis. Due to the heterogeneous and diffuse nature of fat pads, this balance requires a fine and coordinated control of many actors and therefore permanent dialogues between these tissues and the central nervous system. For about two decades, many studies have been devoted to describe the neuro-anatomical and functional complexity involved to ensure this dialogue. Thus, if it is now clearly demonstrated that there is an efferent sympathetic innervation of different fat depots controlling plasticity as well as metabolic functions of the fat pad, the crucial role of sensory innervation capable of detecting local signals informing the central nervous system of the metabolic state of the relevant pads is much more recent. The purpose of this review is to provide the current state of knowledge on this subject.
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Dates et versions

hal-04618371 , version 1 (20-06-2024)

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Anne Lorsignol, Lise Rabiller, Elodie Labit, Louis Casteilla, Luc Pénicaud. The nervous system and adipose tissues: a tale of dialogues. AJP - Endocrinology and Metabolism, 2023, 325 (5), pp.E480-E490. ⟨10.1152/ajpendo.00115.2023⟩. ⟨hal-04618371⟩
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