Article Dans Une Revue International Journal of Gynecological Cancer Année : 2024

Gynecological sarcomas, surgical management: primary, metastatic, and recurrent disease

Résumé

Adult-type gynecological soft tissue and visceral sarcomas are rare tumors, with an estimated incidence of 13% of all sarcomas and 4% of all gynecological malignancies. They most often develop in the uterus (83%), followed by the ovaries (8%), vulva and vagina (5%), and other gynecological organs (2%). The objective of this review is to provide an overview of the current management of gynecological sarcomas, according to international guidelines. The management of gynecological sarcomas should follow the recommendations for the management of soft tissue and visceral sarcomas. Centralizing cases in expert centers improves patient survival, both for the diagnostic phase and for multidisciplinary therapeutic management. In the case of pelvic soft tissue sarcomas, a radiological biopsy is essential before any surgical decision is taken. In the case of a myometrial tumour which may correspond to a sarcoma, if conservative surgery such as myomectomy or morcellation is planned, an ultrasoundguided biopsy with pathological analysis including comparative genomic hybridization analysis must be carried out. In all cases, en bloc surgery, without rupture, is mandatory. Many rare histological subtypes require specific surgical management.
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Dates et versions

hal-04894116 , version 1 (17-01-2025)

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Gwenaël Ferron, Guillaume Bataillon, Alejandra Martinez, Frédéric Chibon, Thibaud Valentin. Gynecological sarcomas, surgical management: primary, metastatic, and recurrent disease. International Journal of Gynecological Cancer, 2024, 34, pp.393-402. ⟨10.1136/ijgc-2023-004582⟩. ⟨hal-04894116⟩
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